Alcohols and polyols
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- (50)
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- (1)
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- (1)
- (26)
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- (1)
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- (1)
- (462)
- (9)
- (46)
- (11)
- (45)
- (6)
- (1)
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- (148)
- (114)
- (7)
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- (1)
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- (1)
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- (1)
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- (20)
- (10)
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- (15)
- (1)
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- (2)
- (2)
- (1)
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- (1)
- (28)
- (29)
- (7)
- (3)
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- (1)
- (36)
- (5)
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- (2)
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- (17)
- (15)
- (4)
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- (2)
- (5)
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- (33)
- (4)
- (2)
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- (8)
- (2)
- (2)
- (8)
- (7)
- (7)
- (2)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (3)
- (1)
- (15)
- (12)
- (1)
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- (2)
- (7)
- (12)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
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- (1)
- (17)
- (2)
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- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (7)
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- (1)
- (1)
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- (1)
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- (60)
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- (1)
- (1)
- (30)
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- (11)
- (82)
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- (3)
- (378)
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- (40)
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Filtered Search Results
Medchemexpress LLC Tauroursodeoxycholate-d5 | 1207294-25-4 | 504.73 | 5 MG
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Tauroursodeoxycholate-d5 is the deuterium labeled Tauroursodeoxycholate, an endoplasmic reticulum (ER) stress inhibitor. It significantly reduces the expression of apoptosis molecules, such as caspase-3 and caspase-12, and also inhibits ERK.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
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Medchemexpress LLC Ginsenoside Rf | 52286-58-5 | 801.01 | 50 MG
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Ginsenoside Rf is a trace component of ginseng root. It is a saponin that rapidly and reversibly inhibits N-type and other high-threshold Ca2+ channels in rat sensory neurons. It is suitable for various laboratory applications.
- Inhibits N-type Ca2+ channels
- Trace component of ginseng root
- Effect largely eliminated by pretreatment with pertussis toxin
- Inhibits Ca2+ channels in hybrid F-11 cell line
- Appears as a white to off-white solid
- Target: N-type calcium channel
- Produces dose-dependent antinociception in mice
- Soluble in DMSO and ethanol for in vitro applications
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Medchemexpress LLC Chaps | 75621-03-3 | C32H58N2O7S | 500 MG
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Chaps is a cholic acid-derived, sulfobetaine-type zwitterionic detergent and micelle-forming agent. It exhibits properties of weak cationic or nonionic surfactants in various solution systems, undergoing micellization and forming small, loose hydrophilic aggregates. This substance is commonly employed in research concerning the separation and purification of membrane proteins.
- Stabilizes mononucleosomes under differing ionic strengths and reduces nucleosome sequence specificity.
- Facilitates the sliding of histone cores along DNA.
- Solubilizes Tamm-Horsfall protein, reducing interference with urinary exosome isolation.
- Maintains vesicle structure and the activity of related proteins.
- Used for recovering native folded fusion proteins and enhancing the binding capacity of GST fusion proteins.
- Restores GST enzyme activity.
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Medchemexpress LLC Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-, (11β)- | 50-24-8 | MFCD00003649 | 99.9% | 360.44 | 500 MG
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Prednisolone is a potent, orally active corticosteroid and a glucocorticoid. It exhibits about four times the anti-inflammatory activity of hydrocortisone while causing less salt and water retention. It can be used for ocular and anti-inflammatory research, and has been shown to inhibit human leukocyte mitosis.
- Potent, orally active corticosteroid
- Glucocorticoid properties
- Exhibits potent anti-inflammatory activity
- Causes less salt and water retention
- Suitable for ocular and anti-inflammatory research
- Inhibits human leukocyte mitosis
- High purity (99.93%)
- White to off-white solid appearance
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eMolecules 2-PHENYLCYCLOHEXANOL | 1444-64-0 | MFCD00064945 | 1g
AstaTech | 2-PHENYLCYCLOHEXANOL | 1g | 526508551 | C12012 | 98.000 | 1444-64-0 | MFCD00064945 | 176.259 | C12H16O
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Medchemexpress LLC Ginsenoside Rg4 | 126223-28-7 | 5 MG
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Ginsenoside Rg4 is an orally active protopanaxatriol type ginsenoside. It can activate PI3K, AKT, and GSK-3β signaling, and inhibit ROS and inflammatory cytokine levels. It is used in research for inflammation, infection, and metabolic diseases like sepsis and lung inflammation.
- Activates PI3K, AKT, and GSK-3β signaling
- Inhibits ROS and inflammatory cytokine levels
- Used for research on inflammation, infection, and metabolic diseases
- Decreases expressions of toll-like receptor (TLR) 4 and TNF-α levels
- Increases cell viability via PI3K/AKT signaling activation
- Promotes hair-inductive properties of DP cells
- Inhibits inflammation and prolongs survival in sepsis models
- Attenuates inflammation in pulmonary inflammation models
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Medchemexpress LLC Gypenoside XLIX | 94987-08-3 | 1047.23 | 5 MG
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Gypenoside XLIX, isolated from Gynostemma pentaphyllum, is a multifunctional bioactive compound. It acts as a PPAR-α agonist and binds to SIRT1, inhibiting TLR4-mediated NF-κB signaling and reducing ROS accumulation.
- Targets SIRT1 to block YAP-NLRP3 activation, improving sepsis-induced cardiomyopathy.
- Inhibits apoptosis, pyroptosis, autophagy, and lipid peroxidation.
- Alleviates sepsis-induced splenic injury, inflammation, and oxidative stress.
- Mitigates sepsis-associated encephalopathy by targeting PPAR-α.
- Prevents acute kidney injury by inhibiting IGFBP7/IGF1R-mediated programmed cell death.
- Inhibits vascular cell adhesion molecule-1 expression in human endothelial cells.
- Used in research for acute liver/lung injury, cardiomyopathy, and acute kidney injury.
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Medchemexpress LLC Glycochenodeoxycholic acid-d4 (Chenodeoxycholylglycine-d4) | 1201918-16-2 | 5 MG
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Glycochenodeoxycholic acid-d4 is the deuterium labeled Glycochenodeoxycholic acid. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) is a bile acid formed in the liver from chenodeoxycholate and glycine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. Glycochenodeoxycholic acid (Chenodeoxycholylglycine) induces hepatocyte apoptosis.
- Deuterium labeled compound.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements can affect the pharmacokinetic and metabolic profiles of drugs.
- Purity: 99.95%.
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Medchemexpress LLC Inositol nicotinate | 6556-11-2 | 98.1% | 50MG
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Inositol nicotinate | 6556-11-2 | 98.1% | 50MG
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Medchemexpress LLC Epi-001 | 227947-06-0 | MFCD02683414 | 99.3% | 394.89 g·mol⁻¹ | C21H27ClO5 | 50 MG
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EPI-001 is a small-molecule research compound that selectively inhibits the androgen receptor (AR) by targeting the amino-terminal domain transactivation unit 5 (Tau-5). It also functions as a selective PPARγ modulator and has demonstrated activity in castration-resistant prostate cancer models. Supplied as a solid analytical standard, it is suitable for biochemical, cell-based, and preclinical in vivo studies when used with recommended formulations and storage.
- Selective AR N-terminal domain inhibitor targeting Tau-5
- Inhibits AR transactivation with reported IC50 ≈ 6 μM
- Also acts as a selective PPARγ modulator
- High supplied purity (~99.3%) suitable for research
- Soluble in DMSO and formulatable for in vivo dosing
- Stable as powder at -20°C for long-term storage
- Available in small research quantities, e.g., 50 MG
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eMolecules Medchem Express / Ginsenoside Rg1 / 5mg / 446274535 / HY-N0045 / / 22427-39-0 / MFCD00210293 / 801.024 / C42H72O14
Medchem Express / Ginsenoside Rg1 / 5mg / 446274535 / HY-N0045 / / 22427-39-0 / MFCD00210293 / 801.024 / C42H72O14
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Cayman Chemical Taurochenodeoxycholc ACDd4 1mg
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An internal standard for the quantification of taurochenodeoxycholic acid by GC- or LC-MS
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eMolecules 1-Phenylcyclohexanol | 1589-60-2 | MFCD00021393 | 1g
Combi-Blocks | 1-Phenylcyclohexanol | 1g | 350781348 | QE-2857 | 98.000 | 1589-60-2 | MFCD00021393 | 176.259 | C12H16O
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Medchemexpress LLC (1beta,11beta,12alpha,15beta)-1,11,12,14,15-pentahydroxy-13,20-epoxypicras-3-ene-2,16-dione | 21499-66-1 | MFCD00221753 | 99.5% | 410.42 g·mol⁻¹ | C20H26O9 | 10 MG
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Bruceine D is a quassinoid natural product used as a research reagent that induces apoptosis and inhibits Notch signaling in cancer cell models. It is supplied as a high-purity solid suitable for in vitro biochemical and cell-based studies.
- High purity: 99.5%.
- Molecular formula: C20H26O9.
- Molecular weight: 410.42 g·mol⁻¹.
- Appearance: white to off-white solid.
- Recommended solvent: DMSO; 100 mg/mL, ultrasonic assistance may be required.
- Storage: store at 4°C protected from light; in solution store at -80°C up to 6 months or -20°C up to 1 month.
- Common applications: in vitro apoptosis assays and cell-based mechanism-of-action studies.
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Medchemexpress LLC JBI-589 | 2308504-22-3 | C29H28FN5O | 1 MG
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JBI-589 is a non-covalent, orally bioavailable, and isoform-selective inhibitor of PAD4. It reduces CXCR2 expression and blocks neutrophil chemotaxis, and has been shown to reduce primary tumor and metastases. This compound enhances the anti-tumor effect of checkpoint inhibitors, making it suitable for cancer research.
- Non-covalent and orally bioavailable
- Isoform-selective inhibitor of PAD4
- Reduces CXCR2 expression and blocks neutrophil chemotaxis
- Inhibits primary tumor growth and metastases
- Enhances anti-tumor effect of checkpoint inhibitors
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